Butler Hospital has been awarded a $12 million, five-year Center of Biomedical Research Excellence (COBRE) grant for research that sheds light on neuropsychiatric disorders and their potential future health implications.
Researchers at Brown University’s Carney Institute for Brain Science have identified a defect in the motor circuit that may serve as an early signal of amyotrophic lateral sclerosis (ALS).
It’s 11 a.m. on Friday, Feb. 21, when Monica Linden, a senior lecturer of neuroscience at Brown University, rings a bell and asks her students to close their eyes, take a deep breath and focus on their posture.
Kathleen Gerlach left her brand new office at Sidney Frank Hall in 2010 to take on a new challenge at the then small, yet rapidly growing Brown Institute for Brain Science.
In honor of Women's History Month and International Women's Day, the Carney Institute invited Sheila E. Blumstein, an outstanding mentor and Brown University professor emerita, to reflect on the changes she witnessed during her 50-year career, as well as her many contributions to creating a more inclusive environment for women scientists.
Considerably more work remained before the discovery would be formally announced with publication in the journal Neuron in the fall of 2017, but the goal was in sight.
Odors have long been used by animals as cues to navigate their environment, but little is known about the neural mechanisms behind the creation of odor memories. Using genetic tagging, a recent study co-authored by Alexander Fleischmann, a neuroscientist at Brown University, identifies specific populations of neurons in the olfactory cortex that are activated in this process.
The researchers developed a computer simulation, in which digital rodents were given a choice of two levers, one of which was associated with the chance of getting a reward. The lever with the reward was the "correct" one, and the lever without was the "wrong" one.
Two decades ago, the Brown Brain Science Program was born through a pioneering grant from the Burroughs Wellcome Fund, supporting graduate students with expertise in the physical sciences and mathematics to tackle problems in brain science. That program grew into the Brown Institute for Brain Science in 2009, which became in 2018 the Robert J. and Nancy D. Carney Institute for Brain Science.
Brain scientists at Brown have bold aspirations. Those aspirations may change our fundamental understanding of the human brain and also transform what’s possible for treating brain-related disorders and diseases.
The VA Career Development Program was established to attract, develop, and retain talented scientists working to improve veteran, health, care, and quality of life.
Visit the UTRA webpage for general information and application instructions. Carney Institute UTRA awards follow all Brown University UTRA guidelines.
Gilad’s extensive leadership portfolio as well as his ongoing research and teaching position him well to build on the considerable strengths of the Center, which nucleates interdisciplinary faculty teams to advance our understanding of the function of neural circuits, using genetic, molecular, and cellular approaches as a foundation.
With a new five-year grant from the National Institutes of Health, the Center for Central Nervous System Function will launch five research projects and develop new analysis tools to advance brain science at Brown.
“If we can understand the neurobiological mechanisms of how the brain is developing differently as a consequence of early-life stress, using our animal model, then we can better understand what types of things we need to do to get children back on the right course for healthy brain development.”
“For years, the BrainGate collaboration has been working to develop the neuroscience and neuroengineering know-how to enable people who have lost motor abilities to control external devices just by thinking about the movement of their own arm or hand,” said Dr. Jaimie Henderson.
Despite that tool’s widespread use, some researchers say a more empirical approach would better serve both patients and the physicians who provide care.